Design of Novel Enzyme Biocatalysts for Industrial Bioprocess

The specificity of enzymatic reactions is crucial for many biological processes. Enzyme catalysts are commonly used in biotechnological processes such as food production, synthetic biology, and drug manufacturing because they provide faster and more efficient production of products. They also have many industrial and commercial applications, such as biodiesel production, wastewater remediation, and medical diagnostics. However, the inherent instability and restricted operating window of enzymes limit their applications. Therefore, there is a need to develop new and more powerful bioenzyme catalysts to meet industrial needs.

With proven expertise in molecular biology and protein engineering and extensive experience in industrial process development, Creative BioMart Consulting is committed to providing a professional development consulting platform for biocatalysts.

How Can We Help?

Creative BioMart Consulting offers consulting services covering every step of the biocatalyst development process, including the design, modification, expression, purification, production, and validation of specific enzymes or microbial systems to catalyze the desired reaction. We can help design novel industrial bioenzyme catalysts for your enhanced enzyme properties, including enzyme activity, thermoelasticity, solvent stability, PH tolerance, substrate-specific product profile, removal of inhibition, and more. Our track record covers a wide range of enzymes and assays, including lipases, proteases, polymerases, laccase, monooxygenases, reductases, sugar isomerases, cellulases, phytases, pectinases, glucose oxidases, amylases, and ethanol dehydrogenases.

For example, with regarding to enzyme activity regulation, we know that factors that affect or control enzyme activity include pH and temperature, and many other factors including genetic enzyme regulation, compartmentalization, substrate concentration, enzyme degradation, altered environmental factors, zymogen modification, covalent modification, metamorphic regulation, and inhibition.

We provide novel biocatalyst designs and artificial biological systems for a variety of customized practical applications. With advanced computational techniques, we can provide valuable leads to guide the development of novel biocatalysts. We provide professional one-stop consulting services including

• Structure-function relationship studies
• Single nucleus active site optimization
• System design for multiple active sites
• Catalytic analysis for validation

What Can We Help You Achieve？

• Efficient synthesis and processing routes
• Reduce costs and turnaround times by minimizing side reactions, by-products and impurities
• Optimize and improve conversion, yield, and selectivity
• Design and setup of self-regenerating or low-maintenance systems

Our Process

Creative BioMart Consulting is committed to being your development partner for the design of novel industrial bioenzyme catalysts. Each of our consulting projects is tailored to your enzyme, your application, and your needs. We aim to facilitate your cost-efficiency and increase your chances of success. We would be happy to learn more about your expertise and work with you, so please feel free to contact us if you are interested in our expertise.